Scientifically Supported Health Benefits of Ginger Root
Anti-inflammatory activity
Gingerols inhibit pro-inflammatory markers like TNF-α, IL-6, and COX-2. Clinical studies have shown ginger extracts to reduce pain and stiffness in individuals with osteoarthritis and rheumatoid arthritis [4]. This makes ginger juice a natural alternative for managing low-grade chronic inflammation.
Digestive support and nausea relief
Ginger is one of the most researched natural remedies for nausea. Meta-analyses confirm that ginger significantly reduces nausea and vomiting in pregnancy, chemotherapy, and postoperative recovery [5]. It also stimulates saliva and bile production, enhancing digestion. It can also been mixed with different juices to increase effect.
Ginger polyphenols scavenge free radicals and upregulate endogenous antioxidant enzymes such as glutathione peroxidase (GPx) and superoxide dismutase (SOD). This helps reduce oxidative stress and cellular damage [6].
Metabolic and blood sugar regulation
Ginger has been shown to lower fasting blood glucose and improve insulin sensitivity in individuals with type 2 diabetes. In one clinical trial, daily ginger supplementation led to significant reductions in HbA1c and insulin resistance scores [7].
Ginger’s ability to reduce platelet aggregation and improve lipid profiles (lower LDL, triglycerides) may support heart health. Some studies suggest ginger may modestly lower blood pressure and enhance circulation [8].
Immune modulation and antimicrobial action
Ginger (also mixed with other juices) compounds have demonstrated antibacterial, antiviral, and antifungal activity. It can inhibit the growth of pathogens like E. coli, Salmonella, and Candida albicans, while also modulating immune cell responses [9].
In sports and physical therapy, ginger has been used to reduce delayed-onset muscle soreness (DOMS) and accelerate recovery after intense exercise. Its analgesic and anti-inflammatory mechanisms are believed to play a key role [10].
References
- Mao, Q.-Q., Xu, X.-Y., Cao, S.-Y., et al. (2019). Bioactive compounds and biological functions of ginger. Phytotherapy Research, 33(3), 592–608.
- Masuda, Y., Kikuzaki, H., Hisamoto, M., et al. (2004). Antioxidative compounds from ginger. Journal of Agricultural and Food Chemistry, 52(9), 2522–2527.
- Stoilova, I., Krastanov, A., Stoyanova, A., et al. (2007). Antioxidant activity of a ginger essential oil. Food Chemistry, 102(3), 764–770.
- Bartels, E. M., Folmer, V. N., Bliddal, H., et al. (2015). Efficacy and safety of ginger in osteoarthritis: A systematic review and meta-analysis of RCTs. Osteoarthritis and Cartilage, 23(1), 13–21.
- Viljoen, E., Visser, J., Koen, N., et al. (2014). A systematic review and meta-analysis of the effect of ginger on nausea and vomiting in pregnancy. Nutrition Journal, 13(1), 20.
- Ghasemzadeh, A., Jaafar, H. Z. E. (2013). Ginger antioxidant activity. International Journal of Molecular Sciences, 14(2), 3288–3303.
- Mozaffari-Khosravi, H., et al. (2014). The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial. Complementary Therapies in Medicine, 22(1), 9–16.
- Alizadeh-Navaei, R., Roozbeh, F., Saravi, M., et al. (2008). Investigation of the effect of ginger on the lipid levels. Saudi Medical Journal, 29(9), 1280–1284.
- Sekiwa, Y., Kubota, K., Kobayashi, A. (2000). Isolation of novel glucosides from ginger and their antimicrobial activity. Bioscience, Biotechnology, and Biochemistry, 64(11), 2462–2466.
- Black, C. D., Herring, M. P., Hurley, D. J., et al. (2010). Ginger (Zingiber officinale) reduces muscle pain after eccentric exercise. Journal of Pain, 11(9), 894–903.