Scientifically Supported Health Benefits
Blood pressure regulation
Phthalides in celery root help relax vascular smooth muscles and promote circulation. Clinical trials show that celery seed extract can reduce both systolic and diastolic blood pressure, offering a natural alternative or complement to pharmaceutical interventions [1].
Fiber and polyphenols in celery support regularity and gut protection. In animal studies, celery extract reduced ulcer formation and gastric inflammation. Its bitter compounds may also stimulate bile secretion and improve digestion of fats [2].
Kidney and urinary tract support
Celery acts as a mild diuretic, increasing urine output and supporting urinary health. Extracts also showed a preventive effect against calcium oxalate kidney stones in rats, suggesting celery may aid in flushing excess salts and preventing stone formation [3].
Anti-inflammatory properties
Apigenin and apiuman reduce systemic inflammation by regulating immune responses. These compounds decrease inflammatory cytokines like IL-1β and increase IL-10, offering support for inflammatory conditions such as arthritis and autoimmune imbalances [4].
Celery extract improves cellular antioxidant status by enhancing enzyme activity and lowering oxidative damage. It stimulates the activity of antioxidant enzymes like SOD, CAT, and GPx, helping to counter oxidative stress from pollution, processed foods, or chronic illness [4].
Cholesterol and lipid metabolism
Studies indicate that celery extract can lower LDL cholesterol and triglycerides while increasing HDL, supporting heart health. This lipid-modulating effect may be due to celery’s fiber, phytosterols, and polyphenol content, which interfere with cholesterol absorption in the intestines [4].
In models of liver toxicity, celery root extract reduced liver enzyme levels and improved tissue structure. This hepatoprotective effect is linked to the antioxidant and anti-inflammatory compounds in celery, making it a gentle but effective support during detoxification protocols [4].
References
- Shayani Rad M., Moohebati M., Mohajeri S.A. (2022). Effect of celery (Apium graveolens) seed extract on hypertension: A randomized, triple-blind, placebo-controlled, cross-over, clinical trial. Phytotherapy Research, 36(7), 2889–2907. DOI: 10.1002/ptr.7469
- Al-Howiriny T., Alsheikh A., Alqasoumi S., et al. (2010). Gastric antiulcer, antisecretory and cytoprotective properties of celery in rats. Pharmaceutical Biology, 48(7), 786–793. DOI: 10.3109/13880200903280026
- Stiani S.N., Syahidah F.M., Fikriani H., Subarnas A., Rusdiana T. (2020). Anticalculi activity of apigenin and celery extract in rats induced by ethylene glycol. Journal of Pharmacy and Bioallied Sciences, 12(1). DOI: 10.4103/jpbs.JPBS_202_19
- Khairullah A.R., Solikhah T.I., Ansori A.N.M., et al. (2021). Review on the pharmacological and health aspects of Apium graveolens (Celery): An update. Systematic Reviews in Pharmacy, 12(1), 606–612. PMC: PMC5871295